Glycoproteins are enormously diverse and mutable macromolecules. In monoclonal antibody development, manipulation of the glycosylation process has critical impacts to stability, activity, antigenicity and pharmacodynamics. Accurately correlating functional features with glycoform structures is essential, and early insight can lead to downstream efficiencies with better decision-making related to the manufacturing process. Yet the inherent heterogeneity and mutability of glycans pose technical challenges in the laboratory.
ABC offers you a team of biopharmaceutical veterans with decades of experience fully characterizing monoclonal antibodies (mAbs) and other recombinant protein biopharmaceuticals. We have the instrumentation necessary to...
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